Sphinganine (dihydrosphingosine) is a natural, saturated, long-chain amino alcohol sphingoid base that acts as a vital precursor for ceramide synthesis and a signaling molecule in eukaryotes. It strengthens the skin barrier, inhibits reductase for hair care, and plays roles in lipid metabolism, antifungal activity, and cellular stress responses.
Chemical Structure: A saturated 18-carbon (d18:0) sphingoid base (2-amino-1,3-octadecanediol). It is the saturated version of sphingosine, which possesses a trans-double bond at C4-C5.
Properties: Highly hydrophobic, crystalline powder, generally synthesized through sphingolipid metabolism or via yeast fermentation for cosmetic applications.
Occurrence: Found in all living organisms, including human cells, where it serves as a backbone for complex sphingolipids.
Cosmetics & Skincare: Used in anti-aging, hydration, and skin barrier repair products. It is considered a skin-identical ingredient.
Hair Care: Formulated into lotions and serums for anti-hair loss and scalp health.
Biochemical Research: Used as an internal standard in mass spectrometry and lipidomics.
We focus on Cosmetic active ingredients, bioactive materials, and plant extracts. In cosmetics, we develop high-purity, high-stability and skin-friendly active ingredients with anti-aging, moisturizing, repairing and brightening effects through biosynthesis. Our team provides safe and stable products for functional food, health care and biomedical fields. We strictly develop and produce high-quality APIs, supporting drug R&D and human health.
Additionally, we have strong capabilities in customized peptide synthesis. Our professional R&D team and advanced synthesis platform provide one-stop customized services covering linear peptides, complex cyclic peptides, peptide encapsulation and modification.




